How Tocotrienol Fight Against Leukemia Cancer Cells?

How Tocotrienol Fight Against Leukemia Cancer Cells?

11 Jul 2022
How Tocotrienol Fight Against Leukemia Cancer Cells?

Leukemia Cancer

Leukemia is one of the deadliest cancers. It has a survival rate of only 61.4% for just 5 years, as stated in a report by the National Cancer Institute, USA! It usually involves the white blood cells. It is a cancer of the body’s blood-forming tissues. Only a few patients survive for more than 10 years due to the common reoccurrence of this cancer.
White blood cells help fight infections and other diseases. In leukemia patients, an excessive number of abnormal white blood cells (WBCs) are produced by the bone marrow. 

First Signs of Leukemia

  • Joint Pain
  • Headaches
  • Heavy Bleeding
  • gasping for Breath
  • Bruising
  • Loss of Appetite
  • Fatigue and Weakness
  • Fever
  • Sweating
  • Sudden Weight Loss
  • Severe Infections

Causes of Leukemia

According to scientists, Leukemia develops from the combination of:

  • Genetic Factors
  • Environmental Factors

How Does Leukemia Form?

When blood cells acquire changes in DNA, it forms Leukemia. Generally, a cell's DNA contains a set of instructions that tell the cell to grow at a set rate and to die at a set time. But in Leukemia, mutations tell the blood cells to keep growing and dividing. Because of this, abnormal blood cells crowd out the healthy body cells in the bone marrow. This leads to fewer healthy blood cells and platelets

Normal Blood Cells vs Leukemia Blood Cells

How Do You Recognise Leukemia Cancer?

Leukemia symptoms are not specific. So, whenever you have any persistent symptoms, go to your doctor.

Several cancer treatments, such as surgery, radiation, and chemotherapy have failed to eradicate cancer entirely. To find a better solution to fight against cancer, doctors and researchers have discovered natural anti-oxidants in the form of Annatto-based Tocotrienols, and Vitamin E which can also be used with other chemotherapeutic drugs that exhibit strong anti-cancer activities against cancer cells. One of these kinds of research is Gamma-Tocotrienol and Simvastatin Synergistically Induce Cytotoxicity In Leukemia Cell Lines, K-562 and HL-60 where it was observed that Gamma-Tocotrienol (an isoform of Vitamin E) and simvastatin (cholesterol-lowering drug) exhibit synergy in the induction of cytotoxicity in K-562 and HL-60 leukemia cell lines. Eannatto has successfully harvested Annatto for Tocotrienols rich in all its isoforms to help Leukemia patients throughout the globe in their fight against blood cancer. It is the small structure and lower molecular weight of tocotrienols due to which they have high antioxidant activity and more mobility. 

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