ALL ABOUT TOCOTRIENOLS VITAMIN E AND THEIR BENEFITS

19 Jan 2022

DISCOVERY OF VITAMIN AND TOCOTRIENOLS

Herbert cLean Evans discovered Vitamin E in 1922 for the first time. But it was initially discovered as a fertility factor. On further research, it was found that it is a fat-soluble organic compound that possesses incomparable antioxidant properties. In nature, Vitamin E exists in two fat-soluble forms Tocopherols and Tocotrienols. Each form has further four isoforms i.e., Alpha, Beta, Gamma, and Delta. Earlier, Tocopherol was consumed most commonly because Vitamin E Tocotrienol sources were very rare in nature.

But a decade ago, Dr. Barrie Tan, came out with a dumbfounding and wonderstruck discovery of Tocotrienols in natural stores like annatto plant, palm, and rice, which was a profound achievement towards the antioxidant therapeutic science for the cure of various chronic illnesses, as Tocotrienols are the proven highly potent antioxidants.

If we go centuries back to the time of ancient Mayans, they used to paint their body with Annatto plant extracts, a storehouse of 100% tocotrienol, because of the natural cosmetic value of the plant. Moreover, it was used as a staple food as well as to treat many ailments too because they had a very deep knowledge of its medicinal value.

SOURCES OF VITAMIN E TOCOTRIENOL

The major sources of tocotrienol are annatto, palm and rice bran. However, it can also be extracted in some quantities from wheat germ, coconut, cocoa, oats, grapefruit seed oil, hazelnuts, olive oil, maize, buckthorn berry, flaxseed oil, rye, sunflower oil, and poppy seed oil. According to various researches, annatto is the source of the most potent form of this vitamin as these provide tocopherol free tocotrienols. It is known that tocopherol tends to interfere very badly with the key therapeutic behaviors of this form. So, if it is 100% pure, then only it will provide us maximum health benefits, thereby making tocotrienol the best vitamin E supplement. Let us compare the various vitamin E sources to know their therapeutic excellency based on the composition.

Source	Alpha-Tocotrienols	Beta-Tocotrienols	Gamma-Tocotrienols	Delta-Tocotrienols	Tocopherol
Annatto	No	No	Yes	Yes	No
Palm	Yes	Yes	Yes	Yes	Yes
Rice	Yes	Yes	Yes	Yes	Yes
Wheat germ	Yes	No	No	No	Yes
Coconut	Yes	No	Yes	Yes	Yes
Cocoa	Yes	No	No	No	Yes

Source: https://eannatto.in/tocotrienols-sources/

DISCOVERY OF ANNATTO VITAMIN E TOCOTRIENOL

As already been discussed, tocotrienol tends to show maximum activity if it is taken solely. This makes the annatto the most effective source because it is the storehouse of tocopherol free tocotrienols. Dr. Barrie Tan has invested his whole life in researching this particular form of vitamin E and is the flag bearer of a number of achievements in this field.
Dr. Barrie Tan’s journey towards tocotrienols started when he visited his friend in Malaysia. His cognizance of the huge antioxidant capabilities of the orange-colored byproduct produced in his amigo’s palm oil manufacturing unit led to the discovery of natural storehouses of the most potent vitamin E form and these are palm, rice, and annatto.
After huge research, he found that Annatto is the most potent source of the purest form of this vitamin as it contains a maximum concentration of Delta Tocotrienols. It has been proven that the Delta Tocotrienol has the maximum bioavailability and incomparable therapeutic benefits among all the eight isoforms of vitamin E. This led to the basis for the synthesis of 100% natural vitamin E supplements such as Eannatto Tocotrienols. AsterVeda Healthcare is making you available the all natural annatto tocotrienols of varied concentrations which one can consume for following purposes:
Eannatto 125mg: One can consume this vitamin E supplement to avail best antioxidant benefits.
Eannatto 300mg: This supplement may help in managing high blood cholesterol levels and chronic inflammations side by side enhancing heart and bone health.
Eannatto 400mg: It may help you in management of various cancers and cell damage caused by radiations.

HEALTH BENEFITS OF TOCOTRIENOL

Most of the following discussed health benefits of this form of vitamin E are due to its outstanding antioxidant properties that means it has an unmatchable tendency to stabilize free radicals. These free radicals are reactive oxygen species that are formed during our regular body activities like exertion, respiration, digestion, mental activities, etc. Such radicals bind to the cell walls and damage them, deteriorating cellular health.

Its three major health benefits are:

It is known to display natural anti-cancer properties by suppressing certain enzyme activity, protein regulation, signaling pathways, and preventing the nutrition supply of cancerous cells. Above that, it helps in arresting cancerous cell proliferation and promoting cell deaths (apoptosis) of the malicious cells. It also helps in preventing a free radical attack on normal cell DNA, thereby helping in the prevention of cancerous conversion of normal cells. Furthermore, it is known to increase the effect of chemo drugs for eliminating tumor cells.
By providing excellent antioxidant cover, this very form of vitamin E helps in promoting rejuvenation, renewal, and repair of damaged skin cells. In this way, it also supports the anti-aging of our skin.
It inhibits the cholesterol synthesizing enzymes, prevents fat oxidation, and promotes declination of bad cholesterol (Low-Density Cholesterol) by 20% enhancing cardiovascular (heart and blood vessels) health. Therefore, it helps in optimizing raised blood pressure issues associated with it. Moreover, its antioxidant effect helps in protecting heart and vessel cells.

Other benefits:

By lowering the synthesis of cholesterol, it helps in maintaining a healthy liver.
It aids in faster wound healing and cell repair by helping in the reduction of inflammatory markers.
Also, this form of vitamin E helps in suppressing cataract progression.
It slows down the bone decalcification process and helps in promoting bone health in postmenopausal females.
It is even beneficial to diabetic patients who have fluctuating blood sugar levels
By preventing nerve cell damage due to free radicals and neuro-toxic insults, it helps in promoting neural health.
By optimizing immune responses, it promotes the body’s immunity.

WHAT ARE THE SIDE EFFECTS OF TOCOTRIENOLS?

It is safe to take tocotrienols but it is always recommended to consult your doctor or health practitioner before taking high doses of tocotrienols, especially when you are on some medication or have any health issue.

DIFFERENCE BETWEEN TOCOTRIENOL AND TOCOPHEROLS

Tocotrienols	Tocopherols
Prepared naturally	Can be prepared synthetically also
High biochemical therapeutic properties	Therapeutically poorer
Molecules have low molecular weight and shorter tails to support more tissue coverage	Molecules have more molecular weight and longer tails resulting in lesser tissue coverage
Molecules move faster resulting in quicker action	Molecules move slowly resulting in delayed action
Display high absorption & bioavailability	Display poorer absorption & bioavailability
Underrated Vitamin E form	Overrated Vitamin E form
Not present in our regular diets. So, supplementation is useful.	Present in our regular diets. So, supplementation is futile.
Do not interfere in tocopherol functioning	Interfere badly in key therapeutic of Tocotrienol
Shows better prevention from neurotoxic insults	Shows poorer prevention from neurotoxic insults

REFERENCES

https://wellbeingnutrition.com/blogs/listing
https://activatednutrients.com/blogs/activated-life
https://barrietan.com/news-events/blog/
https://www.clinicaleducation.org/resources/abstracts/new-study-shows-tocotrienols-reverse-fatty-liver-disease-by-dr-marilyn-arguillas-md-fpcp-fpsg-fpsde/
https://pubmed.ncbi.nlm.nih.gov/29749323/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3148956/
https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4392014/
https://www.medicalnewstoday.com/articles/319689